Michael Crump Selected Research

Guanosine Diphosphate (GDP)

1/2020	Efficacy and safety of stem cell mobilization following gemcitabine, dexamethasone, cisplatin (GDP) salvage chemotherapy in patients with relapsed or refractory lymphoma.
1/2019	A phase I study of romidepsin, gemcitabine, dexamethasone and cisplatin combination therapy in the treatment of peripheral T-cell and diffuse large B-cell lymphoma; the Canadian cancer trials group LY.15 study†.
8/2015	Salvage chemotherapy and autologous stem cell transplantation for transformed indolent lymphoma: a subset analysis of NCIC CTG LY12.
7/2015	Gemcitabine/dexamethasone/cisplatin vs cytarabine/dexamethasone/cisplatin for relapsed or refractory aggressive-histology lymphoma: cost-utility analysis of NCIC CTG LY.12.
11/2014	Randomized comparison of gemcitabine, dexamethasone, and cisplatin versus dexamethasone, cytarabine, and cisplatin chemotherapy before autologous stem-cell transplantation for relapsed and refractory aggressive lymphomas: NCIC-CTG LY.12.
1/2006	Similar response rates and superior early progression-free survival with gemcitabine, dexamethasone, and cisplatin salvage therapy compared with carmustine, etoposide, cytarabine, and melphalan salvage therapy prior to autologous stem cell transplantation for recurrent or refractory Hodgkin lymphoma.

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Michael Crump Research Topics

Disease

30	Lymphoma (Lymphomas) 06/2022 - 11/2003
23	Neoplasms (Cancer) 01/2022 - 08/2002
19	Hodgkin Disease (Hodgkin's Disease) 01/2022 - 12/2003
19	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/2021 - 10/2002
18	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2021 - 08/2002
12	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2020 - 08/2011
9	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2018 - 02/2002
7	B-Cell Lymphoma (Lymphoma, B Cell) 10/2021 - 10/2002
7	Breast Neoplasms (Breast Cancer) 08/2011 - 04/2002
7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2010 - 01/2002
6	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 01/2018 - 03/2006
6	Disease Progression 01/2016 - 05/2003
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2021 - 01/2009
4	Neutropenia 01/2018 - 08/2009
4	Thrombocytopenia (Thrombopenia) 10/2016 - 08/2009
4	Leukemia 04/2010 - 01/2002
3	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2022 - 03/2019
3	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 10/2019 - 11/2003
3	Pathologic Complete Response 01/2016 - 10/2005
3	Alzheimer Disease (Alzheimer's Disease) 03/2011 - 01/2010
2	Melanoma (Melanoma, Malignant) 05/2019 - 10/2017
2	Pneumonia (Pneumonitis) 06/2015 - 08/2011
2	Infections 08/2011 - 10/2002
2	Anemia 08/2009 - 01/2009
1	Sarcopenia 01/2022
1	Inflammation (Inflammations) 10/2021
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 10/2021
1	Exanthema (Rash) 01/2018
1	T-Cell Lymphoma (Lymphoma, T Cell) 01/2018
1	Proteinuria 10/2017
1	Acute Kidney Injury (Acute Renal Failure) 10/2017
1	Nephrotic Syndrome (Syndrome, Nephrotic) 10/2017
1	Infertility (Sterility) 01/2017

Drug/Important Bio-Agent (IBA)

29	Rituximab (Mabthera)FDA Link 12/2021 - 02/2002
10	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 10/2004
9	Gemcitabine FDA Link 01/2020 - 10/2004
8	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 10/2002
8	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 10/2004
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2012
6	Guanosine Diphosphate (GDP)IBA 01/2020 - 01/2006
6	Cytarabine (Cytosar-U)FDA LinkGeneric 07/2015 - 11/2003
5	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 10/2002
5	Prednisone (Sone)FDA LinkGeneric 01/2020 - 10/2002
5	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2014 - 03/2007
4	Bendamustine Hydrochloride FDA Link 11/2021 - 01/2018
4	obinutuzumabIBA 03/2019 - 05/2012
4	Bortezomib (Velcade)FDA Link 05/2013 - 03/2011
3	Brentuximab VedotinIBA 12/2020 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2010
3	Bleomycin (Blenoxane)FDA LinkGeneric 11/2017 - 03/2007
3	Biological ProductsIBA 12/2016 - 03/2008
3	Vinblastine (Vinblastine Sulfate)FDA Link 02/2012 - 02/2006
3	Carmustine (FIVB)FDA Link 04/2010 - 04/2005
2	Amyloid (Amyloid Fibrils)IBA 12/2021 - 01/2011
2	Monoclonal AntibodiesIBA 03/2019 - 10/2015
2	Histone Deacetylase InhibitorsIBA 01/2017 - 01/2016
2	Histones (Histone)IBA 01/2017 - 01/2016
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2017 - 05/2012
2	EnzymesIBA 01/2016 - 08/2002
2	temsirolimus FDA Link 01/2015 - 08/2009
2	TOR Serine-Threonine KinasesIBA 01/2015 - 08/2009
2	Dacarbazine (DIC)FDA LinkGeneric 02/2012 - 03/2007
2	Messenger RNA (mRNA)IBA 01/2011 - 01/2010
2	Insulysin (Insulin-Degrading Enzyme)IBA 01/2011 - 01/2010
2	Etoposide (VP 16)FDA LinkGeneric 01/2006 - 08/2002
1	Alkylating AgentsIBA 12/2021
1	Proteasome InhibitorsIBA 12/2021
1	ibrutinibIBA 11/2021
1	FibrinIBA 10/2021
1	Capsules (Microcapsules)IBA 10/2021
1	Anaplastic Lymphoma KinaseIBA 10/2021
1	glofitamabIBA 01/2021
1	venetoclaxIBA 12/2020
1	duvelisibIBA 10/2019
1	Interleukin-2 (IL2)IBA 05/2019
1	AntibodiesIBA 03/2019
1	romidepsin (FK228)FDA Link 01/2019
1	IpilimumabIBA 10/2017
1	pembrolizumabIBA 10/2017
1	CTLA-4 AntigenIBA 10/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2017
1	mocetinostatIBA 01/2017
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2017

Therapy/Procedure

44	Drug Therapy (Chemotherapy) 01/2022 - 01/2002
43	Therapeutics 06/2022 - 01/2002
16	Stem Cell Transplantation 10/2017 - 02/2002
12	Radiotherapy 01/2019 - 10/2002
6	Salvage Therapy 01/2018 - 01/2006
4	Transplantation 01/2017 - 11/2003
3	Immunotherapy 10/2017 - 02/2002
3	Hematopoietic Stem Cell Transplantation 08/2011 - 01/2006
3	Induction Chemotherapy 10/2005 - 11/2003
3	Adjuvant Chemotherapy 04/2005 - 08/2003
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2004 - 02/2003
1	Combination Drug Therapy (Combination Chemotherapy) 01/2022
1	Breast Implants (Breast Implant) 10/2021
1	Hematopoietic Stem Cell Mobilization 01/2020
1	Organ Transplantation 01/2020
1	Radioimmunotherapy 10/2019
1	Cell- and Tissue-Based Therapy (Cell Therapy) 05/2019